Sunday May 16, 2010


Q: What is the equivalent strength of PO vs IV of Lopressor (Metoprolol)?


Answer: Equivalent maximal beta-blocking effect of Lopressor is achieved with oral and intravenous doses in the ratio of approximately 2.5:1. But be aware - this is not the standard by any means. Literature shows coversion effect ranging anywhere from 2:1 to 5:1.


Previous related pearls:

Labetolol and Hyperkalemia

Ratio of alpha and beta blockade in Labetalol

Atenolol & Renal Failure

Carvediol (Coreg)

Guided dose of labetalol in hypertensive emergency